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<p>Embryonic development transforms a single cell into a structured multicellular organism through coordinated molecular, cellular, and tissue-level processes. In this review, we discuss multiscale modeling studies spanning early embryogenesis from fertilization to organogenesis across diverse systems, emphasizing how distinct computational frameworks have been used to investigate different stages of embryonic morphogenesis. Drawing on complementary animal models, we highlight how multiscale approaches provide mechanistic insights into embryonic patterning and form generation.</p>

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Multiscale Modeling of Embryonic Morphogenesis from Fertilization to Organogenesis

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月15日

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  • Debanik Deb,
  • Orishma Parida,
  • Laasya Naduthota,
  • Bandan Chakrabortty

摘要

Embryonic development transforms a single cell into a structured multicellular organism through coordinated molecular, cellular, and tissue-level processes. In this review, we discuss multiscale modeling studies spanning early embryogenesis from fertilization to organogenesis across diverse systems, emphasizing how distinct computational frameworks have been used to investigate different stages of embryonic morphogenesis. Drawing on complementary animal models, we highlight how multiscale approaches provide mechanistic insights into embryonic patterning and form generation.