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<p>Multicellularity is one of the major evolutionary transitions, and its rise provided the ingredients for the emergence of a biosphere inhabited by complex organisms. Over the last decades, the potential for bioengineering multicellular systems has been instrumental in interrogating nature and exploring novel paths to regeneration, disease, cognition, and behaviour. Here, we provide a list of open problems that encapsulate many of the ongoing and future challenges in the field and suggest conceptual approaches that may facilitate progress.</p>

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Open problems in synthetic multicellularity

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2024年12月31日

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  • Ricard Solé,
  • Núria Conde–Pueyo,
  • Jordi Pla–Mauri,
  • Jordi Garcia–Ojalvo,
  • Nuria Montserrat,
  • Michael Levin

摘要

Multicellularity is one of the major evolutionary transitions, and its rise provided the ingredients for the emergence of a biosphere inhabited by complex organisms. Over the last decades, the potential for bioengineering multicellular systems has been instrumental in interrogating nature and exploring novel paths to regeneration, disease, cognition, and behaviour. Here, we provide a list of open problems that encapsulate many of the ongoing and future challenges in the field and suggest conceptual approaches that may facilitate progress.