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<p>β-casomorphin-7 (βCM-7) is a bioactive peptide released after the digestion of β-casein A1 variant, mostly found in European cow breeds’ milk. This review explores the occurrence, characteristics, identification, techno-functionality, and the potential health effects of βCM-7. It displays opioid-like properties because of its affinity for μ-opioid receptors, affecting both food texture and biological functions. βCM-7 has potential advantages on immune and gastrointestinal health; however, concerns persist regarding its adverse effects.</p>

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β-casomorphin-7: a review of occurrence, identification, techno-functionality, and effects on human health

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月21日

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  • Abdelmoneim H. Ali,
  • Mayssa Hachem,
  • Zain Najjar,
  • Shao-Quan Liu,
  • Gafar Babatunde Bamigbade,
  • Mutamed Ayyash

摘要

β-casomorphin-7 (βCM-7) is a bioactive peptide released after the digestion of β-casein A1 variant, mostly found in European cow breeds’ milk. This review explores the occurrence, characteristics, identification, techno-functionality, and the potential health effects of βCM-7. It displays opioid-like properties because of its affinity for μ-opioid receptors, affecting both food texture and biological functions. βCM-7 has potential advantages on immune and gastrointestinal health; however, concerns persist regarding its adverse effects.