Scholarlink

<p>Accurate subthalamic beta activity could guide deep brain stimulation programming in Parkinson’s disease, but bipolar recordings complicate contact selection. In 39 patients, we validated three methods to estimate pseudo-monopolar beta power. Distance-weighted methods (Euclidean, Strelow) agreed consistently with the externalized “ground-truth” beta distribution. Maximal beta power across 20s windows was more stable in ring than in directional channels. Beta-contacts from all methods aligned with clinically active stimulation contacts one year after surgery.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Identifying maximal beta power from directional subthalamic local field potentials in Parkinson’s disease

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年5月8日

查看全文
  • Jennifer K. Behnke,
  • Robert L. Peach,
  • Moritz Gerster,
  • Richard M. Köhler,
  • Jeroen G. V. Habets,
  • Johannes L. Busch,
  • Varvara Mathiopoulou,
  • Jonathan Kaplan,
  • Lucia K. Feldmann,
  • Juliette Vivien,
  • Chi Wang Ip,
  • Gerd-Helge Schneider,
  • Katharina Faust,
  • Patricia Krause,
  • Andrea A. Kühn

摘要

Accurate subthalamic beta activity could guide deep brain stimulation programming in Parkinson’s disease, but bipolar recordings complicate contact selection. In 39 patients, we validated three methods to estimate pseudo-monopolar beta power. Distance-weighted methods (Euclidean, Strelow) agreed consistently with the externalized “ground-truth” beta distribution. Maximal beta power across 20s windows was more stable in ring than in directional channels. Beta-contacts from all methods aligned with clinically active stimulation contacts one year after surgery.