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<p>Despite its potential to modulate brain and network activity, non-invasive brain stimulation is not yet clinically applied for treating Parkinson’s disease. We here review recent findings that illustrate how various non-invasive stimulation techniques can modify pathological and compensatory activities. Due to unavoidable heterogeneities and low effect sizes of the reviewed studies, a deeper understanding of the mechanisms of action will be critical for refining clinical effectiveness and generating consistent results.</p>

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Non-invasive brain stimulation to modulate neural activity in Parkinson’s disease

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年4月5日

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  • Manuel Bange,
  • Rick C. G. Helmich,
  • Aparna A. Wagle Shukla,
  • Günther Deuschl,
  • Muthuraman Muthuraman

摘要

Despite its potential to modulate brain and network activity, non-invasive brain stimulation is not yet clinically applied for treating Parkinson’s disease. We here review recent findings that illustrate how various non-invasive stimulation techniques can modify pathological and compensatory activities. Due to unavoidable heterogeneities and low effect sizes of the reviewed studies, a deeper understanding of the mechanisms of action will be critical for refining clinical effectiveness and generating consistent results.