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<p>This review evaluates BFRT as a novel countermeasure against multisystem deconditioning (muscle atrophy, bone loss, cardiovascular impairment) during long-duration space missions. BFRT combines low-load exercise with vascular occlusion, mimicking high-intensity benefits while reducing equipment needs. We synthesize evidence for BFRT’s efficacy in microgravity analogs, discusses implementation challenges (equipment adaptation, safety protocols, sex-specific responses), and highlight its potential as a space-efficient adjunct to current exercise regimens, informing future mission planning.</p>

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Blood flow restriction training in microgravity: a review of multisystem physiological benefits and implementation challenges for long-duration space missions

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月7日

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  • Mingzhen Hu,
  • Wei Li,
  • Qiushi Yin,
  • Yuqing Liu,
  • Lin Chen,
  • Qin Ru,
  • Guodong Xu,
  • Yuxiang Wu

摘要

This review evaluates BFRT as a novel countermeasure against multisystem deconditioning (muscle atrophy, bone loss, cardiovascular impairment) during long-duration space missions. BFRT combines low-load exercise with vascular occlusion, mimicking high-intensity benefits while reducing equipment needs. We synthesize evidence for BFRT’s efficacy in microgravity analogs, discusses implementation challenges (equipment adaptation, safety protocols, sex-specific responses), and highlight its potential as a space-efficient adjunct to current exercise regimens, informing future mission planning.