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<p>This review highlights how gut microbiota regulates intestinal stem cell function. Weaning stress disrupts this balance, causing intestinal injury in piglets. However, targeted nutritional interventions can modulate the gut microbiota to restore ISC function and repair tissue damage. Understanding this microbe-ISC interaction provides new, effective strategies to improve gut health and alleviate weaning-induced injury in animals.</p>

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Microbial regulation of intestinal stem cell function: implications for alleviating intestinal injury of weaned piglets

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年4月3日

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  • Bo Song,
  • Feilong Deng,
  • Hui Jiang,
  • Meimei Zhang,
  • Jiangchao Zhao,
  • Jianmin Chai,
  • Ying Li

摘要

This review highlights how gut microbiota regulates intestinal stem cell function. Weaning stress disrupts this balance, causing intestinal injury in piglets. However, targeted nutritional interventions can modulate the gut microbiota to restore ISC function and repair tissue damage. Understanding this microbe-ISC interaction provides new, effective strategies to improve gut health and alleviate weaning-induced injury in animals.