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<p><i>Enterococcus faecalis</i>, a non-oral nosocomial pathogen, intriguingly ranks among the most frequently retrieved species from polymicrobial infections of dental root canals. This review integrates findings from the latest omics approaches, alongside emerging evidence of <i>E. faecalis</i> interactions within oral polymicrobial communities, to refine our understanding of its role in these infections. Herein, <i>E. faecalis</i> emerges as an ecologically invasive species and a catalyst of the pathogenicity of entire communities.</p>

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A polymicrobial perspective into the ecological role of Enterococcus faecalis in dental root canal infections

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年5月22日

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  • Ana Parga,
  • Jade Mattu,
  • Georgios N. Belibasakis,
  • Kimberly A. Kline,
  • Julian G. Leprince,
  • Daniel Manoil

摘要

Enterococcus faecalis, a non-oral nosocomial pathogen, intriguingly ranks among the most frequently retrieved species from polymicrobial infections of dental root canals. This review integrates findings from the latest omics approaches, alongside emerging evidence of E. faecalis interactions within oral polymicrobial communities, to refine our understanding of its role in these infections. Herein, E. faecalis emerges as an ecologically invasive species and a catalyst of the pathogenicity of entire communities.