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<p>Oral potentially malignant disorders (OPMDs) and gastrointestinal precancerous lesions (GPLs) are major public health concerns because of their potential to progress to cancer. Probiotics, prebiotics, and engineered probiotics can positively influence the prevention and management of OPMDs and GPLs. This review aims to comprehensively review the application status of probiotics, prebiotics and engineered probiotics in OPMDs and GPLs, explore their potential mechanisms of action, and anticipate their future clinical use.</p>

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Probiotics and prebiotics: new treatment strategies for oral potentially malignant disorders and gastrointestinal precancerous lesions

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年4月8日

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  • Zhuwei Huang,
  • Jiaye Zhu,
  • Xiangwen Bu,
  • Shulai Lu,
  • Yixian Luo,
  • Ting Liu,
  • Ning Duan,
  • Wenmei Wang,
  • Yong Wang,
  • Xiang Wang

摘要

Oral potentially malignant disorders (OPMDs) and gastrointestinal precancerous lesions (GPLs) are major public health concerns because of their potential to progress to cancer. Probiotics, prebiotics, and engineered probiotics can positively influence the prevention and management of OPMDs and GPLs. This review aims to comprehensively review the application status of probiotics, prebiotics and engineered probiotics in OPMDs and GPLs, explore their potential mechanisms of action, and anticipate their future clinical use.