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<p>Lifespan extension has not prevented age-related decline. We propose that diet acts as a molecular modulator of aging, influencing inflammation, the microbiome, and systemic resilience. Biological age markers and AI-powered multi-omics reveal actionable dietary targets, including food-derived signals and Nutrition Dark Matter. We highlight precision nutrition and the EIT Food Healthy Aging Think &amp; Do Tank as pathways to align science, policy, and practice for healthy aging.</p>

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Modulating biological aging with food-derived signals: a systems and precision nutrition perspective

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月20日

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  • Carsten Carlberg,
  • Andreas Blüthner,
  • Irini Schoeman-Giziakis,
  • Annemarie Oosting,
  • Luca Cocolin

摘要

Lifespan extension has not prevented age-related decline. We propose that diet acts as a molecular modulator of aging, influencing inflammation, the microbiome, and systemic resilience. Biological age markers and AI-powered multi-omics reveal actionable dietary targets, including food-derived signals and Nutrition Dark Matter. We highlight precision nutrition and the EIT Food Healthy Aging Think & Do Tank as pathways to align science, policy, and practice for healthy aging.