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<p>To quantify the hospital burden of short-term wildfire-specific fine particulate matter (PM<sub>2.5</sub>), we linked 184.5 million patient-level hospitalizations across 449 Brazilian regions from 2000–2019 with daily wildfire-specific and non-wildfire PM<sub>2.5</sub> estimates at 0.25° resolution. Using wind-driven variation in wildfire-specific PM<sub>2.5</sub> within a space-time-stratified case-crossover framework, we estimated the effects of exposure on hospitalization costs and length of stay. Each 1 µg/m<sup>3</sup> increase in wildfire-specific PM<sub>2.5</sub> was associated with higher hospitalization costs for all-cause, respiratory, and cardiovascular diseases by 0.36%, 1.59%, and 0.25%, respectively, and longer stays by 0.63%, 1.72%, and 0.68%. Asthma and heart failure showed the largest cost increases, while asthma and pneumonia showed the largest increases in length of stay. Overall, wildfire-specific PM<sub>2.5</sub> accounted for US$755.6 million in hospitalization costs and 30.8 million hospital days, with stronger relative effects among individuals aged 0–19 years and higher burdens in central-west Brazil.</p>

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Causal effects of wildfire PM2.5 on hospital costs and length of stay in Brazil

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月7日

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  • Ke Ju,
  • Rongbin Xu,
  • Wenzhong Huang,
  • Yiwen Zhang,
  • Tingting Ye,
  • Wenhua Yu,
  • Zhengyu Yang,
  • Gongbo Chen,
  • Yanming Liu,
  • Pei Yu,
  • Shuang Zhou,
  • Yao Wu,
  • Bo Wen,
  • Zhihu Xu,
  • Paulo H. N. Saldiva,
  • Micheline S. Z. S. Coelho,
  • Jiangning Song,
  • Shanshan Li,
  • Yuming Guo

摘要

To quantify the hospital burden of short-term wildfire-specific fine particulate matter (PM2.5), we linked 184.5 million patient-level hospitalizations across 449 Brazilian regions from 2000–2019 with daily wildfire-specific and non-wildfire PM2.5 estimates at 0.25° resolution. Using wind-driven variation in wildfire-specific PM2.5 within a space-time-stratified case-crossover framework, we estimated the effects of exposure on hospitalization costs and length of stay. Each 1 µg/m3 increase in wildfire-specific PM2.5 was associated with higher hospitalization costs for all-cause, respiratory, and cardiovascular diseases by 0.36%, 1.59%, and 0.25%, respectively, and longer stays by 0.63%, 1.72%, and 0.68%. Asthma and heart failure showed the largest cost increases, while asthma and pneumonia showed the largest increases in length of stay. Overall, wildfire-specific PM2.5 accounted for US$755.6 million in hospitalization costs and 30.8 million hospital days, with stronger relative effects among individuals aged 0–19 years and higher burdens in central-west Brazil.