<p>Fire is a pervasive biogeographic process that shapes biodiversity globally and is now experiencing unprecedented changes. Despite well documented impacts of fires on biodiversity, we do not know where biodiversity might be most vulnerable to changing fire regimes. We leverage recent advancements in fire forecasting and species distribution modeling to assess the exposure of bird species richness, community uniqueness, and functional richness to altered fire regimes in the western United States. We find that 55-58% of biodiversity hotspots are classified as “refugia”, where high biodiversity intersects with predicted low severity burn areas. In contrast, 24-30% of biodiversity hotspots are classified as “areas of concern”, where high biodiversity intersected with predicted high severity burn areas. Over half (52-60%) of “areas of concern” occur in geographies with historically low-severity fire regimes; a fire regime mismatch indicating a potential threat to biodiversity. We find that species with a preference for high-density vegetation and with shallower beak depth are most likely to be exposed to high severity fire, indicating a potential for habitat losses for species with these traits. Our findings reinforce calls for targeted management to reduce impacts of future fire where it is predicted to be outside the historical range of variation.</p>