Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge
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期刊论文
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发表日期:
2025年7月8日
- Maximilian Zenk,
- Ujjwal Baid,
- Sarthak Pati,
- Akis Linardos,
- Brandon Edwards,
- Micah Sheller,
- Patrick Foley,
- Alejandro Aristizabal,
- David Zimmerer,
- Alexey Gruzdev,
- Jason Martin,
- Russell T. Shinohara,
- Annika Reinke,
- Fabian Isensee,
- Santhosh Parampottupadam,
- Kaushal Parekh,
- Ralf Floca,
- Hasan Kassem,
- Bhakti Baheti,
- Siddhesh Thakur,
- Verena Chung,
- Kaisar Kushibar,
- Karim Lekadir,
- Meirui Jiang,
- Youtan Yin,
- Hongzheng Yang,
- Quande Liu,
- Cheng Chen,
- Qi Dou,
- Pheng-Ann Heng,
- Xiaofan Zhang,
- Shaoting Zhang,
- Muhammad Irfan Khan,
- Mohammad Ayyaz Azeem,
- Mojtaba Jafaritadi,
- Esa Alhoniemi,
- Elina Kontio,
- Suleiman A. Khan,
- Leon Mächler,
- Ivan Ezhov,
- Florian Kofler,
- Suprosanna Shit,
- Johannes C. Paetzold,
- Timo Loehr,
- Benedikt Wiestler,
- Himashi Peiris,
- Kamlesh Pawar,
- Shenjun Zhong,
- Zhaolin Chen,
- Munawar Hayat,
- Gary Egan,
- Mehrtash Harandi,
- Ece Isik Polat,
- Gorkem Polat,
- Altan Kocyigit,
- Alptekin Temizel,
- Anup Tuladhar,
- Lakshay Tyagi,
- Raissa Souza,
- Nils D. Forkert,
- Pauline Mouches,
- Matthias Wilms,
- Vishruth Shambhat,
- Akansh Maurya,
- Shubham Subhas Danannavar,
- Rohit Kalla,
- Vikas Kumar Anand,
- Ganapathy Krishnamurthi,
- Sahil Nalawade,
- Chandan Ganesh,
- Ben Wagner,
- Divya Reddy,
- Yudhajit Das,
- Fang F. Yu,
- Baowei Fei,
- Ananth J. Madhuranthakam,
- Joseph Maldjian,
- Gaurav Singh,
- Jianxun Ren,
- Wei Zhang,
- Ning An,
- Qingyu Hu,
- Youjia Zhang,
- Ying Zhou,
- Vasilis Siomos,
- Giacomo Tarroni,
- Jonathan Passerrat-Palmbach,
- Ambrish Rawat,
- Giulio Zizzo,
- Swanand Ravindra Kadhe,
- Jonathan P. Epperlein,
- Stefano Braghin,
- Yuan Wang,
- Renuga Kanagavelu,
- Qingsong Wei,
- Yechao Yang,
- Yong Liu,
- Krzysztof Kotowski,
- Szymon Adamski,
- Bartosz Machura,
- Wojciech Malara,
- Lukasz Zarudzki,
- Jakub Nalepa,
- Yaying Shi,
- Hongjian Gao,
- Salman Avestimehr,
- Yonghong Yan,
- Agus S. Akbar,
- Ekaterina Kondrateva,
- Hua Yang,
- Zhaopei Li,
- Hung-Yu Wu,
- Johannes Roth,
- Camillo Saueressig,
- Alexandre Milesi,
- Quoc D. Nguyen,
- Nathan J. Gruenhagen,
- Tsung-Ming Huang,
- Jun Ma,
- Har Shwinder H. Singh,
- Nai-Yu Pan,
- Dingwen Zhang,
- Ramy A. Zeineldin,
- Michal Futrega,
- Yading Yuan,
- Gian Marco Conte,
- Xue Feng,
- Quan D. Pham,
- Yong Xia,
- Zhifan Jiang,
- Huan Minh Luu,
- Mariia Dobko,
- Alexandre Carré,
- Bair Tuchinov,
- Hassan Mohy-ud-Din,
- Saruar Alam,
- Anup Singh,
- Nameeta Shah,
- Weichung Wang,
- Chiharu Sako,
- Michel Bilello,
- Satyam Ghodasara,
- Suyash Mohan,
- Christos Davatzikos,
- Evan Calabrese,
- Jeffrey Rudie,
- Javier Villanueva-Meyer,
- Soonmee Cha,
- Christopher Hess,
- John Mongan,
- Madhura Ingalhalikar,
- Manali Jadhav,
- Umang Pandey,
- Jitender Saini,
- Raymond Y. Huang,
- Ken Chang,
- Minh-Son To,
- Sargam Bhardwaj,
- Chee Chong,
- Marc Agzarian,
- Michal Kozubek,
- Filip Lux,
- Jan Michálek,
- Petr Matula,
- Miloš Ker^kovský,
- Tereza Kopr^ivová,
- Marek Dostál,
- Václav Vybíhal,
- Marco C. Pinho,
- James Holcomb,
- Marie Metz,
- Rajan Jain,
- Matthew D. Lee,
- Yvonne W. Lui,
- Pallavi Tiwari,
- Ruchika Verma,
- Rohan Bareja,
- Ipsa Yadav,
- Jonathan Chen,
- Neeraj Kumar,
- Yuriy Gusev,
- Krithika Bhuvaneshwar,
- Anousheh Sayah,
- Camelia Bencheqroun,
- Anas Belouali,
- Subha Madhavan,
- Rivka R. Colen,
- Aikaterini Kotrotsou,
- Philipp Vollmuth,
- Gianluca Brugnara,
- Chandrakanth J. Preetha,
- Felix Sahm,
- Martin Bendszus,
- Wolfgang Wick,
- Abhishek Mahajan,
- Carmen Balaña,
- Jaume Capellades,
- Josep Puig,
- Yoon Seong Choi,
- Seung-Koo Lee,
- Jong Hee Chang,
- Sung Soo Ahn,
- Hassan F. Shaykh,
- Alejandro Herrera-Trujillo,
- Maria Trujillo,
- William Escobar,
- Ana Abello,
- Jose Bernal,
- Jhon Gómez,
- Pamela LaMontagne,
- Daniel S. Marcus,
- Mikhail Milchenko,
- Arash Nazeri,
- Bennett Landman,
- Karthik Ramadass,
- Kaiwen Xu,
- Silky Chotai,
- Lola B. Chambless,
- Akshitkumar Mistry,
- Reid C. Thompson,
- Ashok Srinivasan,
- J. Rajiv Bapuraj,
- Arvind Rao,
- Nicholas Wang,
- Ota Yoshiaki,
- Toshio Moritani,
- Sevcan Turk,
- Joonsang Lee,
- Snehal Prabhudesai,
- John Garrett,
- Matthew Larson,
- Robert Jeraj,
- Hongwei Li,
- Tobias Weiss,
- Michael Weller,
- Andrea Bink,
- Bertrand Pouymayou,
- Sonam Sharma,
- Tzu-Chi Tseng,
- Saba Adabi,
- Alexandre Xavier Falcão,
- Samuel B. Martins,
- Bernardo C. A. Teixeira,
- Flávia Sprenger,
- David Menotti,
- Diego R. Lucio,
- Simone P. Niclou,
- Olivier Keunen,
- Ann-Christin Hau,
- Enrique Pelaez,
- Heydy Franco-Maldonado,
- Francis Loayza,
- Sebastian Quevedo,
- Richard McKinley,
- Johannes Slotboom,
- Piotr Radojewski,
- Raphael Meier,
- Roland Wiest,
- Johannes Trenkler,
- Josef Pichler,
- Georg Necker,
- Andreas Haunschmidt,
- Stephan Meckel,
- Pamela Guevara,
- Esteban Torche,
- Cristobal Mendoza,
- Franco Vera,
- Elvis Ríos,
- Eduardo López,
- Sergio A. Velastin,
- Joseph Choi,
- Stephen Baek,
- Yusung Kim,
- Heba Ismael,
- Bryan Allen,
- John M. Buatti,
- Peter Zampakis,
- Vasileios Panagiotopoulos,
- Panagiotis Tsiganos,
- Sotiris Alexiou,
- Ilias Haliassos,
- Evangelia I. Zacharaki,
- Konstantinos Moustakas,
- Christina Kalogeropoulou,
- Dimitrios M. Kardamakis,
- Bing Luo,
- Laila M. Poisson,
- Ning Wen,
- Martin Vallières,
- Mahdi Ait Lhaj Loutfi,
- David Fortin,
- Martin Lepage,
- Fanny Morón,
- Jacob Mandel,
- Gaurav Shukla,
- Spencer Liem,
- Gregory S. Alexandre,
- Joseph Lombardo,
- Joshua D. Palmer,
- Adam E. Flanders,
- Adam P. Dicker,
- Godwin Ogbole,
- Dotun Oyekunle,
- Olubunmi Odafe-Oyibotha,
- Babatunde Osobu,
- Mustapha Shu’aibu Hikima,
- Mayowa Soneye,
- Farouk Dako,
- Adeleye Dorcas,
- Derrick Murcia,
- Eric Fu,
- Rourke Haas,
- John A. Thompson,
- David Ryan Ormond,
- Stuart Currie,
- Kavi Fatania,
- Russell Frood,
- Amber L. Simpson,
- Jacob J. Peoples,
- Ricky Hu,
- Danielle Cutler,
- Fabio Y. Moraes,
- Anh Tran,
- Mohammad Hamghalam,
- Michael A. Boss,
- James Gimpel,
- Deepak Kattil Veettil,
- Kendall Schmidt,
- Lisa Cimino,
- Cynthia Price,
- Brian Bialecki,
- Sailaja Marella,
- Charles Apgar,
- Andras Jakab,
- Marc-André Weber,
- Errol Colak,
- Jens Kleesiek,
- John B. Freymann,
- Justin S. Kirby,
- Lena Maier-Hein,
- Jake Albrecht,
- Peter Mattson,
- Alexandros Karargyris,
- Prashant Shah,
- Bjoern Menze,
- Klaus Maier-Hein,
- Spyridon Bakas
摘要
Computational competitions are the standard for benchmarking medical image analysis algorithms, but they typically use small curated test datasets acquired at a few centers, leaving a gap to the reality of diverse multicentric patient data. To this end, the Federated Tumor Segmentation (FeTS) Challenge represents the paradigm for real-world algorithmic performance evaluation. The FeTS challenge is a competition to benchmark (i) federated learning aggregation algorithms and (ii) state-of-the-art segmentation algorithms, across multiple international sites. Weight aggregation and client selection techniques were compared using a multicentric brain tumor dataset in realistic federated learning simulations, yielding benefits for adaptive weight aggregation, and efficiency gains through client sampling. Quantitative performance evaluation of state-of-the-art segmentation algorithms on data distributed internationally across 32 institutions yielded good generalization on average, albeit the worst-case performance revealed data-specific modes of failure. Similar multi-site setups can help validate the real-world utility of healthcare AI algorithms in the future.