Scholarlink

Purpose <p>To compare the SITA Standard 24-2 and SITA Faster 24-2 C tests in patients with chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy and those at high risk.</p> Methods <p>A prospective, cross-sectional study of 75 participants who underwent CQ/HCQ retinopathy screening using the SITA Standard 24-2, SITA Faster 24-2 C, optical coherence tomography, fundus autofluorescence, and a dilated eye examination on the same day. Participants were categorized into retinopathy and non-retinopathy groups by graders. The agreement between the two visual field (VF) tests was assessed using Bland-Altman plots.</p> Results <p>Among the 75 participants, 10 (13.3%) were diagnosed with CQ/HCQ retinopathy. Bland-Altman plots show good agreement in median deviation (MD), pattern standard deviation (PSD), and central mean sensitivity (CMS) between tests. The concordance coefficient was 0.89-0.93. Significant differences in MD, PSD, and CMS were observed between the retinopathy and non-retinopathy groups for both VF tests (<i>P</i> ≤ 0.02). However, within each group, the results of both VF tests were comparable across all parameters (<i>P</i> = 0.12–0.79), except for PSD in the non-retinopathy group. The SITA Faster 24-2 C test had a significantly shorter testing duration.</p> Conclusions <p>The SITA Standard 24-2 and SITA Faster 24-2 C tests showed similar efficacy and strongly positive agreement in screening for CQ/HCQ retinopathy. However, the SITA Faster 24-2 C minimized the testing time. The addition of testing points within the central 10-degree field did not enhance the detection of CQ/HCQ retinopathy in the Thai population.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Agreements between 24-2 and 24-2 C test grids for chloroquine/hydroxychloroquine retinopathy patients and high-risk patients

  • 期刊论文

  • 发表日期：

    2026年5月5日

查看全文
  • Chananchida Wongwachira,
  • Disorn Suwajanakorn,
  • Wijak Kongwattananon,
  • Sunee Chansangpetch,
  • Anita Manassakorn,
  • Pear Ferreira Pongsachareonnont,
  • Rath Itthipanichpong,
  • Visanee Tantisevi,
  • Prin Rojanapongpun,
  • Kitiya Ratanawongphaibul

摘要

Purpose

To compare the SITA Standard 24-2 and SITA Faster 24-2 C tests in patients with chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy and those at high risk.

Methods

A prospective, cross-sectional study of 75 participants who underwent CQ/HCQ retinopathy screening using the SITA Standard 24-2, SITA Faster 24-2 C, optical coherence tomography, fundus autofluorescence, and a dilated eye examination on the same day. Participants were categorized into retinopathy and non-retinopathy groups by graders. The agreement between the two visual field (VF) tests was assessed using Bland-Altman plots.

Results

Among the 75 participants, 10 (13.3%) were diagnosed with CQ/HCQ retinopathy. Bland-Altman plots show good agreement in median deviation (MD), pattern standard deviation (PSD), and central mean sensitivity (CMS) between tests. The concordance coefficient was 0.89-0.93. Significant differences in MD, PSD, and CMS were observed between the retinopathy and non-retinopathy groups for both VF tests (P ≤ 0.02). However, within each group, the results of both VF tests were comparable across all parameters (P = 0.12–0.79), except for PSD in the non-retinopathy group. The SITA Faster 24-2 C test had a significantly shorter testing duration.

Conclusions

The SITA Standard 24-2 and SITA Faster 24-2 C tests showed similar efficacy and strongly positive agreement in screening for CQ/HCQ retinopathy. However, the SITA Faster 24-2 C minimized the testing time. The addition of testing points within the central 10-degree field did not enhance the detection of CQ/HCQ retinopathy in the Thai population.