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Purpose <p>This study aimed to investigate age-related trends and associations of biometric parameters in the Korean population.</p> Methods <p>We retrospectively reviewed the patients who underwent IOLMaster 700 scanning between November 2022 and December 2024. We investigated the correlations between age and ocular biometric parameters—axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), corneal power (K), white-to-white distance (WTW), and vitreous chamber depth (VCD).</p> Results <p>2223 eyes (mean age: 71.46 ± 11.12 years) were included. Pearson’s correlation analysis showed that AL, ACD, and VCD were moderately negatively correlated with age (<i>p</i> &lt; 0.001), whereas LT was strongly positively correlated with age (<i>p</i> &lt; 0.001). However, multiple linear regression analysis revealed that age was positively associated with LT and ACD (<i>p</i> &lt; 0.001 and <i>p</i> = 0.038, respectively), whereas it was negatively associated with VCD, CCT, K, and WTW (all <i>p</i> &lt; 0.001). AL was not independently associated with age in this model (<i>p</i> = 0.185).</p> Conclusion <p>Age was independently associated with an increase in LT and ACD and a decrease in VCD, CCT, K, and WTW in the Korean population, whereas AL was not independently associated with age. These findings enhance our understanding of ocular aging and associated biometric patterns.</p>

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Large-scale study of ocular biometry in Korean adults: age-related trends and associations

  • 期刊论文

  • 发表日期：

    2026年3月4日

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  • Seongmi Kim,
  • Ahnul Ha,
  • Ji Woong Chang,
  • Jinho Jeong,
  • Ki Tae Nam

摘要

Purpose

This study aimed to investigate age-related trends and associations of biometric parameters in the Korean population.

Methods

We retrospectively reviewed the patients who underwent IOLMaster 700 scanning between November 2022 and December 2024. We investigated the correlations between age and ocular biometric parameters—axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), corneal power (K), white-to-white distance (WTW), and vitreous chamber depth (VCD).

Results

2223 eyes (mean age: 71.46 ± 11.12 years) were included. Pearson’s correlation analysis showed that AL, ACD, and VCD were moderately negatively correlated with age (p < 0.001), whereas LT was strongly positively correlated with age (p < 0.001). However, multiple linear regression analysis revealed that age was positively associated with LT and ACD (p < 0.001 and p = 0.038, respectively), whereas it was negatively associated with VCD, CCT, K, and WTW (all p < 0.001). AL was not independently associated with age in this model (p = 0.185).

Conclusion

Age was independently associated with an increase in LT and ACD and a decrease in VCD, CCT, K, and WTW in the Korean population, whereas AL was not independently associated with age. These findings enhance our understanding of ocular aging and associated biometric patterns.