Scholarlink

Introduction <p>To assess the outcomes of pars plana vitrectomy (PPV) in patients with complications related to retinal focal nodular gliosis (FNGs), also known as vasoproliferative tumours.</p> Material/subjects and methods <p>This retrospective case series included 22 patients who underwent PPV for the management of FNG-related complications at Moorfields Eye Hospital between 2012 and 2024. We collected and analysed the patient demographics, clinical features and surgical outcomes.</p> Results <p>The mean age was 50.59 years (SD 14.5) at presentation and 52.59 years (SD 13.9) at the time of surgery. The most common indications for surgery were epiretinal membrane (<i>n</i> = 9, 40.9%) and vitreous haemorrhage (<i>n</i> = 8, 36.4%). Fifteen eyes (68.2%) were treatment-naïve, while five (22.7%) had previously undergone ruthenium plaque radiotherapy. The median follow-up period was 34 months (IQR 6.0–62.2). The median preoperative visual acuity was 1.15 logMAR (IQR 0.67–2.40), which significantly improved to 0.4 logMAR (IQR 0.17–1.0) at the last follow-up visit (<i>p</i> &lt; 0.01). Postoperative complications were not observed in 14 patients (63.6%), while cystoid macular oedema was the most common complication following vitrectomy (13.6%, <i>n</i> = 3). Three patients required FNG-related re-operation for rhegmatogenous retinal detachment, macular hole, and epiretinal membrane. All FNGs were inactive at the last follow-up visit.</p> Discussion <p>Vitreous haemorrhage and epiretinal membrane are the most common indications for surgery in patients with FNG. PPV demonstrates favourable functional and anatomic outcomes, though it is worth noting a 13.6% re-operation rate for complications. Significant visual improvement and effective tumour control are also recorded in the long-term.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The role of pars plana vitrectomy in managing complications related to retinal focal nodular gliosis (vasoproliferative tumours)

  • 期刊论文

  • 发表日期：

    2025年12月24日

查看全文
  • Asterios Diafas,
  • Nikolaos Dervenis,
  • Amr Wassef,
  • Genovefa Machairoudia,
  • Lyndon DaCruz,
  • Mandeep S. Sagoo,
  • Hassan Elkayal

摘要

Introduction

To assess the outcomes of pars plana vitrectomy (PPV) in patients with complications related to retinal focal nodular gliosis (FNGs), also known as vasoproliferative tumours.

Material/subjects and methods

This retrospective case series included 22 patients who underwent PPV for the management of FNG-related complications at Moorfields Eye Hospital between 2012 and 2024. We collected and analysed the patient demographics, clinical features and surgical outcomes.

Results

The mean age was 50.59 years (SD 14.5) at presentation and 52.59 years (SD 13.9) at the time of surgery. The most common indications for surgery were epiretinal membrane (n = 9, 40.9%) and vitreous haemorrhage (n = 8, 36.4%). Fifteen eyes (68.2%) were treatment-naïve, while five (22.7%) had previously undergone ruthenium plaque radiotherapy. The median follow-up period was 34 months (IQR 6.0–62.2). The median preoperative visual acuity was 1.15 logMAR (IQR 0.67–2.40), which significantly improved to 0.4 logMAR (IQR 0.17–1.0) at the last follow-up visit (p < 0.01). Postoperative complications were not observed in 14 patients (63.6%), while cystoid macular oedema was the most common complication following vitrectomy (13.6%, n = 3). Three patients required FNG-related re-operation for rhegmatogenous retinal detachment, macular hole, and epiretinal membrane. All FNGs were inactive at the last follow-up visit.

Discussion

Vitreous haemorrhage and epiretinal membrane are the most common indications for surgery in patients with FNG. PPV demonstrates favourable functional and anatomic outcomes, though it is worth noting a 13.6% re-operation rate for complications. Significant visual improvement and effective tumour control are also recorded in the long-term.