RETRACTED ARTICLE: Ultrasound biomicroscopy qualitative and quantitative signs of phacoantigenic uveitis

To describe the ultrasound biomicroscopy (UBM) diagnostic featuresin patients suspected of experiencing chronic inflammation due to phacoantigenicuveitis

This single-center study enrolled patients referred to the UveitisDepartment of Cleveland Clinic Abu Dhabi for chronic anterior uveitis andtraumatic cataract. Patients’ demographics, causes and dates of theinciting traumatic event, and ophthalmic findings were recorded. 20-MHz UBMassessment of the status of the anterior capsule and the crystalline lens wasperformed. Then, cataract surgery was performed using a single technique.Comparison of the anterior capsule and lens status by clinical, UBM, andintraoperative evaluation.

Forty eyes with phacoantigenic uveitis were considered. Theslit-lamp examination could identify interruption of the anterior capsule in 20%of the eyes and liquefied sinking lens material in 10%. An intra-operativedefect in the anterior capsule was documented in 87.5% of eyes. UBM imagingshowed anterior capsule irregularity in 63.3% of eyes and confirmed the presenceof anterior capsule defects in 47.5% and lens matter herniating into theanterior chamber in 15%. Hypoechogenic lacunae within the cataractous lens weredetected in 12.5% of eyes. For UBM, sensitivity and specificity values were82.86% (95% CI: 66.35–93.44) and 100% (95% CI: 47.82–100),respectively. Positive and negative predictive values for UBM were 100% (95% CI:88.06–100) and 45.45% (95% CI: 28.69–63.32), respectively. Theoverall diagnostic accuracy of UBM was 85% [95% CI: 70.16–94.29].

Ultrasound Biomicroscopy (UBM) is essential for assessing suspectedanterior capsule ruptures in phacoantigenic uveitis cases.