Scholarlink

<p>Patients undergoing radical cystectomy face substantial nutritional challenges, yet dietary intake patterns and their adequacy remain poorly defined. In this prospective observational study of 25 ERAS-managed patients, energy and protein adequacy was low during the first postoperative week, while body weight remained stable – likely influenced by fluid retention. Significant weight loss emerged by day 14 (–2.3%; <i>p</i> &lt; 0.001), which increased by day 30 (–5.3%; <i>p</i> &lt; 0.001), despite dietetic follow-up and improvements in dietary intake. Patients requiring nasogastric decompression experienced greater weight loss than those without (–7.2% vs. –3.9%; <i>p</i> = 0.004), suggesting an association with nutritional deterioration. We conclude that early weight trajectory alone may not be a good indicator of nutritional status. Evaluating dietary intake, nutritional symptoms, and body composition including fluid balance is likely required for optimal clinical decision-making. This underscores the importance of individualized, symptom-responsive strategies, including consideration of supplemental nutrition in patients with persistent intolerance.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Not just about weight: Identifying hidden nutritional vulnerability after radical cystectomy

  • 期刊论文

  • 发表日期：

    2025年12月10日

查看全文
  • Jakob Højgaard Hundebøll,
  • Alberte Fisker Olesen,
  • Irene Wessel,
  • Faidon Magkos,
  • Alicia Martin Poulsen,
  • Ane Rytter

摘要

Patients undergoing radical cystectomy face substantial nutritional challenges, yet dietary intake patterns and their adequacy remain poorly defined. In this prospective observational study of 25 ERAS-managed patients, energy and protein adequacy was low during the first postoperative week, while body weight remained stable – likely influenced by fluid retention. Significant weight loss emerged by day 14 (–2.3%; p < 0.001), which increased by day 30 (–5.3%; p < 0.001), despite dietetic follow-up and improvements in dietary intake. Patients requiring nasogastric decompression experienced greater weight loss than those without (–7.2% vs. –3.9%; p = 0.004), suggesting an association with nutritional deterioration. We conclude that early weight trajectory alone may not be a good indicator of nutritional status. Evaluating dietary intake, nutritional symptoms, and body composition including fluid balance is likely required for optimal clinical decision-making. This underscores the importance of individualized, symptom-responsive strategies, including consideration of supplemental nutrition in patients with persistent intolerance.