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Cytosporones Y and Z, new antifungal polyketides produced by the fungal strain Trichoderma sp. FKI-6626

  • Haruki Azami,
  • Yoshihiro Watanabe,
  • Hiroki Kojima,
  • Yurika Yoshida,
  • Sayaka Ban,
  • Kenichi Nonaka,
  • Takashi Yaguchi,
  • Masato Iwatsuki

摘要

Two new antifungal polyketides, named cytosporones Y (1) and Z (2), were discovered from the cultured broth of Trichoderma sp. FKI-6626. Their structures were elucidated by MS and NMR analysis. Both compounds exhibited antifungal activity against five Aspergillus species, the causative agents of aspergillosis.