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Fluorophore-glucan conjugate for oligosaccharide sensing in aqueous media

  • Hiroki Kurohara,
  • Yumiko Hori,
  • Munenori Numata,
  • Gaku Fukuhara

摘要

The ability to sense saccharides in aqueous media using conventional supramolecular approaches was a turning point in modern chemistry. Herein, we performed oligosaccharide sensing using fluorophore-modified branched glucans. Through the newly developed glucan-based chemosensor, acarbose sensing was achieved in a selectively and sensitive manner. The optical properties and morphological changes in the chemosensor were investigated, revealing that the globule-to-coaggregation process plays a key role in oligosaccharide sensing.