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<p><b>Aim</b> To review the impact of glucagon-like peptide-1 (GLP-1) receptor agonists on the facial profile and oral cavity and to highlight their relevance to dental practice.</p><p><b>Methods</b> A narrative review of the medical and dental literature was undertaken, alongside review of UK regulatory guidance, to assess the effects of GLP-1 receptor agonists on oral and facial tissues.</p><p><b>Results</b> GLP-1 receptor agonists are increasingly prescribed in the UK for the management of obesity and diabetes. Despite their widespread use, there is limited dental literature addressing their effects on the facial profile and oral cavity. Consequently, dentists and dental care professionals are increasingly likely to encounter patients taking these medications without clear guidance on associated oral or facial implications.</p><p><b>Conclusion</b> As prescribing of GLP-1 receptor agonists increases, awareness of their potential oral and facial effects is essential for dental practitioners. Improved knowledge will support appropriate patient management and highlight the need for further dental-focused research.</p>

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Glucagon-like peptide-1 receptor agonists: a review of the literature from a dental perspective

  • 期刊论文

  • 发表日期：

    2026年2月13日

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  • Jill O´Driscoll,
  • Grant McIntyre

摘要

Aim To review the impact of glucagon-like peptide-1 (GLP-1) receptor agonists on the facial profile and oral cavity and to highlight their relevance to dental practice.

Methods A narrative review of the medical and dental literature was undertaken, alongside review of UK regulatory guidance, to assess the effects of GLP-1 receptor agonists on oral and facial tissues.

Results GLP-1 receptor agonists are increasingly prescribed in the UK for the management of obesity and diabetes. Despite their widespread use, there is limited dental literature addressing their effects on the facial profile and oral cavity. Consequently, dentists and dental care professionals are increasingly likely to encounter patients taking these medications without clear guidance on associated oral or facial implications.

Conclusion As prescribing of GLP-1 receptor agonists increases, awareness of their potential oral and facial effects is essential for dental practitioners. Improved knowledge will support appropriate patient management and highlight the need for further dental-focused research.