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Background <p>Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital cardiac anomaly. As a viable alternative for complex anatomical variants, the outcomes of single-ventricle palliation (SVP) in ccTGA patients remain poorly defined.</p> Methods <p>We conducted a single-center retrospective analysis of ccTGA patients who underwent SVP between January 2004 and December 2020.</p> Results <p>A total of 73 patients were included. Patients with ccTGA undergoing SVP demonstrated excellent early and mid-term outcomes, with no observed mortality and freedom from MAEs of 96.0%, 93.6%, and 78.0% at 5, 10, and 15 years postoperatively, respectively.</p> Conclusions <p>SVP can achieve excellent early and mid-term outcomes in carefully selected ccTGA patients. When complex biventricular repair is not feasible, SVP represents a safe and effective alternative.</p> Impact <p><UnorderedList Mark="Bullet"> <ItemContent> <p>Single-ventricle palliation can achieve excellent outcomes in selected congenitally corrected transposition of the great arteries.</p> </ItemContent> <ItemContent> <p>When complex biventricular repair is not feasible, SVP represents a safe and effective alternative.</p> </ItemContent> </UnorderedList></p>

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Congenitally corrected transposition of the great arteries: outcomes after single ventricle palliation

  • 期刊论文

  • 发表日期：

    2025年11月18日

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  • Tianyu Chen,
  • Zewen Chen,
  • Miao Tian,
  • Hailong Qiu,
  • Jianzheng Cen,
  • Shusheng Wen,
  • Jimei Chen,
  • Xiaobing Liu,
  • Jian Zhuang

摘要

Background

Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital cardiac anomaly. As a viable alternative for complex anatomical variants, the outcomes of single-ventricle palliation (SVP) in ccTGA patients remain poorly defined.

Methods

We conducted a single-center retrospective analysis of ccTGA patients who underwent SVP between January 2004 and December 2020.

Results

A total of 73 patients were included. Patients with ccTGA undergoing SVP demonstrated excellent early and mid-term outcomes, with no observed mortality and freedom from MAEs of 96.0%, 93.6%, and 78.0% at 5, 10, and 15 years postoperatively, respectively.

Conclusions

SVP can achieve excellent early and mid-term outcomes in carefully selected ccTGA patients. When complex biventricular repair is not feasible, SVP represents a safe and effective alternative.

Impact

Single-ventricle palliation can achieve excellent outcomes in selected congenitally corrected transposition of the great arteries.

When complex biventricular repair is not feasible, SVP represents a safe and effective alternative.