Abstract <p>In this commentary, we provide additional context to interpret the findings reported on the&#xa0;manuscript by Liu et al., “Neuroprotective effects of vitamin C on hypoxic-ischemic brain injury in neonatal mice” published in this issue of Pediatric Research.</p> Impact <p><UnorderedList Mark="Bullet"> <ItemContent> <p>Vitamin C is an anti-oxidant with anti-inflammatory effects, which may be neuroprotective against neonatal hypoxic-ischemic (HI) brain injury in a preterm mouse model</p> </ItemContent> <ItemContent> <p>Several experimental caveats include the timing of intervention, model use and side effects.</p> </ItemContent> <ItemContent> <p>We provide additional context to the reader in the interpretation of the data.</p> </ItemContent> </UnorderedList></p>

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Vitamin C for neuroprotection in neonatal encephalopathy

  • Raul Chavez-Valdez,
  • Nazli Kuter,
  • Srishti Jayakumar

摘要

Abstract

In this commentary, we provide additional context to interpret the findings reported on the manuscript by Liu et al., “Neuroprotective effects of vitamin C on hypoxic-ischemic brain injury in neonatal mice” published in this issue of Pediatric Research.

Impact

Vitamin C is an anti-oxidant with anti-inflammatory effects, which may be neuroprotective against neonatal hypoxic-ischemic (HI) brain injury in a preterm mouse model

Several experimental caveats include the timing of intervention, model use and side effects.

We provide additional context to the reader in the interpretation of the data.