Global cross-sectional survey on neonatal pharmacologic sedation and analgesia practices and pain assessment tools: impact of the sociodemographic index (SDI)

期刊论文
发表日期：

2024年2月13日

查看全文

Cristina Arribas,
Giacomo Cavallaro,
Juan-Luis Gonzalez,
Carolina Lagares,
Genny Raffaeli,
Anne Smits,
Sinno H. P. Simons,
Eduardo Villamor,
Karel Allegaert,
Felipe Garrido,
Abigail Kusi Amponsah,
Agnes van den Hoogen,
Alexandra Ullsten,
Angela Amigoni,
Anna Axelin,
Annakaija Palomaa,
Aomesh Bhatt,
Arild Rønnestad,
Beatrice Olsson Duse,
Bente Johanne Vederhus,
Bente Silnes Tandberg,
Bert Joosten,
Caroline Hartley,
Charalampos Kotidis,
Charles Christoph Roehr,
Christ-Jan van Ganzewinkel,
Cristina Arribas,
Daniela Sofia Horta Machado,
Daniëlla Roofthooft,
Elisabeth Norman,
Emma Olsson,
Eugene Dempsey,
Evalotte Mörelius,
Felipe Garrido,
Flore Le Marechal,
Francesca Sperotto,
Genny Raffaeli,
Gerbrich van den Bosch,
Guðrún Kristjánsdóttir,
Hanna Ahl,
Hans Jørgen Stensvold,
Helle Haslund-Thomsen,
Janne Weiss,
Jannicke Hanne Andresen,
Jean-Michel Roue,
Joke Wielenga,
Judith ten Barge,
Katrin Klebermass-Schrehof,
Laila Kristoffersen,
Laura Moschino,
Lene Lyngstad,
Liam Mahoney,
Luke Baxter,
Magdalena Panek,
Manon Tauzin,
Maria Gradin,
Mariaana Mäki-Asiala,
Marsha Campbell-Yeo,
Martina Carlsen Misic,
Mathilde Baudat,
Mats Eriksson,
Máximo Vento,
Monique van Dijk,
Naomi Meesters,
Natalia Toumbourou,
Nunzia Decembrino,
Paola Lago,
Pia Lundqvist,
Randi Dovland Andersen,
Rebeccah Slater,
Ricardo Carbajal,
Rikke Louise Stenkjær,
Robert B. Flint,
Samir El Abdouni,
Scott Montgomery,
Serdar Beken,
Sezin Ünal,
Shalini Ojha,
Shellie Robinson,
Sigríður María Atladóttir,
Sinno H. P. Simons,
Sofie Pirlotte,
Solfrid Steinnes,
Swantje Völler,
Tarja Pölkki,
Tiina Ukkonen,
Tom Stiris,
Xavier Durrmeyer

摘要

Background

There is variability in the use of sedatives and analgesics in neonatal intensive care units (NICUs). We aimed to investigate the use of analgesics and sedatives and the management of neonatal pain and distress.

Methods

This was a global, prospective, cross-sectional study. A survey was distributed May–November 2022. The primary outcome of this research was to compare results between countries depending on their socio-sanitary level using the sociodemographic index (SDI). We organized results based on geographical location.

Results

The survey collected 1304 responses, but we analyzed 924 responses after database cleaning. Responses from 98 different countries were analyzed. More than 60% of NICUs reported having an analgosedation guideline, and one-third of respondents used neonatal pain scales in more than 80% of neonates. We found differences in the management of sedation and analgesia between NICUs on different continents, but especially between countries with different SDIs. Countries with a higher SDI had greater availability of and adherence to analgosedation guidelines, as well as higher rates of analgosedation for painful or distressing procedures. Countries with different SDIs reported differences in analgosedation for neonatal intubation, invasive ventilation, and therapeutic hypothermia, among others.

Conclusions

Socio-economic status of countries impacts on neonatal analgosedation management.

Impact

There is significant variability in the pain management practices in neonates.

There is a lack of knowledge related to how neonatal pain management practices differ between regions.

Sociodemographic index is a key factor associated with differences in neonatal pain management practices across global regions.