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<p>A design strategy for NIR-emitting lanthanide nanoparticles resolves the fundamental tension between core-shell passivation and dye sensitization. By engineering a Yb³⁺-doped interlayer as an active energy relay between surface-bound ICG and an heavily Er³⁺-doped core, a ~ 2000-fold brightness enhancement is achieved, enabling high-contrast in vivo vascular imaging.</p>

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Catch and relay: brighter near-infrared photoluminescence in lanthanide-based nanoparticles

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年6月22日

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  • Liyan Ming,
  • Riccardo Marin

摘要

A design strategy for NIR-emitting lanthanide nanoparticles resolves the fundamental tension between core-shell passivation and dye sensitization. By engineering a Yb³⁺-doped interlayer as an active energy relay between surface-bound ICG and an heavily Er³⁺-doped core, a ~ 2000-fold brightness enhancement is achieved, enabling high-contrast in vivo vascular imaging.