Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib

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• 发表日期：

  2024年7月31日

• Ariel Leyte-Vidal,
• RosaAnna DeFilippis,
• Ian R. Outhwaite,
• Isabelle Kwan,
• Ji Young Lee,
• Carlyn Leavitt,
• Kaeli B. Miller,
• Delphine Rea,
• Aziz M. Rangwala,
• Kevin Lou,
• Suhana Patel,
• Ailin Alvarez,
• Kevan M. Shokat,
• Ivet Bahar,
• Markus A. Seeliger,
• Neil P. Shah