Background <p>Defective newborn screening (NBS) specimens require repeat collection, potentially delaying care and increasing healthcare costs.</p> Objective <p>To reduce unsatisfactory NBS rates in the well-baby nursery from 35% to &lt;10% over 12-months through establishment of a dedicated specimen collection team.</p> Methods <p>Staff education, establishment of a specimen collection team, and pre-dispatch review were implemented. Outcome measure was the unsatisfactory specimen rate. Process measure was the proportion of specimens collected by the specimen collection team. Balancing measure was the proportion of specimens obtained &gt;48 h after birth.</p> Results <p>During the intervention period (<i>n</i> = 2395), unsatisfactory specimen rate decreased to 5.3% with special cause variation, exceeding our target, and was sustained for 18 months (<i>n</i> = 3668). The specimen collection team collected all specimens. Specimens obtained &gt;48 h after birth decreased from 6.5% to 4.7%.</p> Conclusion <p>NBS specimen collection by trained staff with pre-dispatch review can improve specimen quality without impacting the timeliness of screening.</p>

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Improving the quality of newborn screening dry blood spot specimens in the nursery

  • Diksha Shrestha,
  • Kelechi Ikeri,
  • Vicki Curtis,
  • Karen Williams,
  • Victoria Humphries,
  • Michael Zayek

摘要

Background

Defective newborn screening (NBS) specimens require repeat collection, potentially delaying care and increasing healthcare costs.

Objective

To reduce unsatisfactory NBS rates in the well-baby nursery from 35% to <10% over 12-months through establishment of a dedicated specimen collection team.

Methods

Staff education, establishment of a specimen collection team, and pre-dispatch review were implemented. Outcome measure was the unsatisfactory specimen rate. Process measure was the proportion of specimens collected by the specimen collection team. Balancing measure was the proportion of specimens obtained >48 h after birth.

Results

During the intervention period (n = 2395), unsatisfactory specimen rate decreased to 5.3% with special cause variation, exceeding our target, and was sustained for 18 months (n = 3668). The specimen collection team collected all specimens. Specimens obtained >48 h after birth decreased from 6.5% to 4.7%.

Conclusion

NBS specimen collection by trained staff with pre-dispatch review can improve specimen quality without impacting the timeliness of screening.