Cannabis use, preterm birth, and small for gestational age: findings from the national birth defects prevention study
摘要
As the prevalence of cannabis use continues to increase among women of reproductive age, studies exploring the impact of in utero cannabis exposure on birth outcomes are warranted.
Study designUsing data from the National Birth Defects Prevention Study, logistic regression was used to assess the relationship between maternal self-report of cannabis use during early pregnancy and 1) preterm birth, and 2) being born SGA. Patterns of cannabis use during the first six months of pregnancy were also assessed.
ResultsThree percent of the sample (n = 324) reported cannabis use in early pregnancy. A slight majority (56%) of users ceased the use of cannabis after the second month of pregnancy. No significant association was observed between cannabis use and preterm birth (aOR = 1.27, 95% CI: 0.88–1.83) or SGA (aOR = 1.00, 95% CI: 0.68–1.47).
ConclusionCannabis use in early pregnancy was not significantly associated with preterm birth or SGA in this sample.