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Objective <p>To quantify inter-center variation (ICV) in length of stay (LOS) among surviving infants with jejunal (JA) or ileal atresia (IA).</p> Study design <p>Children’s Hospitals Neonatal Consortium’s database was used to identify infants with JA or IA. After excluding infants with abdominal wall defects, survivors’ hospital LOS was modeled as a function of center using generalized linear models with log link for gamma distribution.</p> Results <p>There were 1134 and 808 infants with JA and IA, respectively. LOS had significant ICV in unadjusted (JA: 5.4 [IQR 3.7,9.9] weeks; IA: 4.3 [IQR 2.4,11.4] weeks) and multivariable analyses (JA: 4+ fold difference (6.5–31.5 week); <i>p</i> &lt; 0.001 IA: 8+ fold difference (1.7–14.6 weeks); <i>p</i> &lt; 0.001) with modifiable risk factors including cholestasis, ostomy creation, blood stream infection, and residual bowel length &lt;55 cm.</p> Conclusion <p>Risk-adjusted ICV in LOS was observed in infants with JA and IA, which exposes opportunities for improvements in outcomes for infants with intestinal atresia.</p>

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Inter-center variations in length of hospitalization for infants with congenital jejunal or ileal atresia

  • 期刊论文

  • 发表日期：

    2025年11月27日

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  • Katie A. Huff,
  • Isabella Zaniletti,
  • Kera McNelis,
  • Alan Ladd,
  • Abeer Azzuqa,
  • Carl H. Coghill,
  • Daniel T. Robinson,
  • Muralidhar H. Premkumar,
  • Patricia W. Denning,
  • Jae Kim,
  • Mark R. Corkins,
  • Andrea Adler,
  • Darren Bodkin,
  • Jeffrey Rudolph,
  • Ashley Moore,
  • Katie M. Strobel,
  • Michael A. Padula,
  • Theresa R. Grover,
  • Karna Murthy,
  • Sujir Pritha Nayak,
  • Anthony Piazza,
  • Gregory Sysyn,
  • Ashley Lucke,
  • Molly Pont,
  • Allison Black,
  • Carl Coghill,
  • Anne Hansen,
  • Eugenia Pallotto,
  • Karna Murthy,
  • Gustave Falciglia,
  • Beth Haberman,
  • Ceyda Acun,
  • Thomas Bartman,
  • Sushmita Yallapragada,
  • Lina Chalak,
  • Danielle Smith,
  • Stephanie Bourque,
  • Girija Natarajan,
  • Annie Chi,
  • Yvette Johnson,
  • Annmarie Gotiolo,
  • Kristina Reber,
  • Rebecca Rose,
  • Julie Lindower,
  • Julie Weiner,
  • Laura Carroll,
  • Rachel Chapman,
  • Nina Menda,
  • Mark Weems,
  • Ann Downey,
  • Joanne Lagatta,
  • Priscilla Joe,
  • Trent Tipple,
  • Patricia Williams,
  • Nicole Birge,
  • Michel Mikhael,
  • Narendra Dereddy,
  • Rajan Wadhawan,
  • Aaron Weiss,
  • Michael Padula,
  • Vilarmis Quinones,
  • Pam Griffiths,
  • Toby Yanowitz,
  • Ellen Bendel-Stenzel,
  • Con Yee Ling,
  • Mark Speziale,
  • Robert DiGeronimo,
  • Elizabeth Jacobsen,
  • Beverly Brozanski,
  • Rakesh Rao,
  • Ann Downey,
  • Linda Van Marter,
  • Kyong-Soon Lee,
  • Billie Lou Short,
  • Kevin Sullivan,
  • Cherrie Welch

摘要

Objective

To quantify inter-center variation (ICV) in length of stay (LOS) among surviving infants with jejunal (JA) or ileal atresia (IA).

Study design

Children’s Hospitals Neonatal Consortium’s database was used to identify infants with JA or IA. After excluding infants with abdominal wall defects, survivors’ hospital LOS was modeled as a function of center using generalized linear models with log link for gamma distribution.

Results

There were 1134 and 808 infants with JA and IA, respectively. LOS had significant ICV in unadjusted (JA: 5.4 [IQR 3.7,9.9] weeks; IA: 4.3 [IQR 2.4,11.4] weeks) and multivariable analyses (JA: 4+ fold difference (6.5–31.5 week); p < 0.001 IA: 8+ fold difference (1.7–14.6 weeks); p < 0.001) with modifiable risk factors including cholestasis, ostomy creation, blood stream infection, and residual bowel length <55 cm.

Conclusion

Risk-adjusted ICV in LOS was observed in infants with JA and IA, which exposes opportunities for improvements in outcomes for infants with intestinal atresia.