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Objective <p>To evaluate the effect of age correction up to 36 months of age for growth assessments of extremely preterm (&lt;28 weeks) and very preterm (28 to &lt;32 weeks) infants.</p> Study Design <p>This longitudinal analysis used data from the Preterm Infant Multicenter Growth Study (2001–2014).</p> Results <p>1,416 children were included (Median gestational age = 27 weeks). Chronological age-based weight, height, and head circumference z-scores were consistently lower than those based on corrected age for all ages (0, 4, 8, 21 and 36 months) by up to −5.2 (95% confidence interval −5.4, −5.1) z-scores for length at term. Using chronological age, higher proportions of children were misclassified as having suboptimal growth (up to 72.9% misdiagnosed as stunted and 89.8% misdiagnosed as underweight at term).</p> Conclusion <p>For extremely and very preterm children, age correction is required for all growth measures through 36 months of corrected age.</p>

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Preterm growth assessment: the latest findings on age correction

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年1月16日

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  • Seham Elmrayed,
  • Susan Dai,
  • Abhay Lodha,
  • Manoj Kumar,
  • Tanis R. Fenton

摘要

Objective

To evaluate the effect of age correction up to 36 months of age for growth assessments of extremely preterm (<28 weeks) and very preterm (28 to <32 weeks) infants.

Study Design

This longitudinal analysis used data from the Preterm Infant Multicenter Growth Study (2001–2014).

Results

1,416 children were included (Median gestational age = 27 weeks). Chronological age-based weight, height, and head circumference z-scores were consistently lower than those based on corrected age for all ages (0, 4, 8, 21 and 36 months) by up to −5.2 (95% confidence interval −5.4, −5.1) z-scores for length at term. Using chronological age, higher proportions of children were misclassified as having suboptimal growth (up to 72.9% misdiagnosed as stunted and 89.8% misdiagnosed as underweight at term).

Conclusion

For extremely and very preterm children, age correction is required for all growth measures through 36 months of corrected age.