Oxygenation associated with cord management strategies among preterm infants <32 weeks gestation during the transition period

期刊论文
发表日期：

2024年10月11日

查看全文

Catherine Peterson,
Lucia Ferrer,
Shashank Sanjay,
Debra Poeltler,
Satyan Lakshminrusimha,
Anup C. Katheria

摘要

Objective

Compare changes in SpO₂ and FiO₂ post-birth among preterm infants after delayed cord clamping (DCC), umbilical cord milking (UCM) or early cord clamping (ECC).

Study Design

Retrospective study of infants <32 weeks gestation born between 2014 and 2021. ECC was clamping 0–59 s, DCC was clamping ≥60 s after delivery, UCM defined as milking the intact umbilical cord several times before clamping.

Results

Of 463 infants; 257 received DCC, 168 received UCM, 38 received ECC. UCM infants had higher median SpO₂ values at 4-(79% UCM vs 69% DCC, p = 0.027) and 5-(85% UCM vs 80% DCC, p = 0.023) minutes after-birth compared to DCC. DCC and UCM infants required lower FiO₂ levels in the first 5-minutes compared to ECC infants (DCC 0.38 ± 0.17, UCM 0.40 ± 0.20 vs ECC 0.51 ± 0.27, p’s <0.001).

Conclusion

The proportion of infants achieving SpO₂ ≥ 80% by 5 min was similar in all groups, FiO₂ needed to achieve this goal was higher in ECC infants.