The impact of implementation of oral dextrose gel on the incidence of multiple hypoglycemia events in the well newborn nursery

Evaluate the impact of 40% oral dextrose gel (DG) for management of neonatal hypoglycemia (NH) on the incidence of multiple hypoglycemic events in the well-baby nursery.

A retrospective chart review of 738 at-risk infants in 2 cohorts before (Cohort 1) and after (Cohort 2) DG implementation. Primary outcome was the incidence of ≥2 hypoglycemic episodes. Secondary outcomes were number of lowest median glucose level, and incidence of NICU admission.

There were 384 and 354 at-risk newborns in Cohorts 1 & 2. The incidence of developing ≥2 hypoglycemia episodes significantly decreased following DG implementation [62(42.5%) vs 29(25.9%), p = 0.0058]. There were no differences in lowest glucose level [37 (14–45) vs 37 (10–45), p = 0.31], and NICU admission rate [31 (21.2%) vs 21 (18.8%), p = 0.62].

Implementation of DG lowers the incidence of subsequent hypoglycemia episodes.