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Health-related quality of life at age 10 years in children born extremely preterm

  • Catherine Call,
  • Ali Oran,
  • T. Michael O’Shea,
  • Elizabeth T. Jensen,
  • Jean A. Frazier,
  • Ruben Vaidya,
  • Jeffrey Shenberger,
  • Semsa Gogcu,
  • Michael E. Msall,
  • Sohye Kim,
  • Isha Jalnapurkar,
  • Rebecca C. Fry,
  • Rachana Singh

摘要

Objective

To evaluate the association between prenatal maternal health and socioeconomic status (SES) and health-related quality of life (QoL) among 10-year-old children born extremely preterm.

Design/ methods

Retrospective analysis of the Extremely Low Gestational Age Newborns (ELGAN) Study cohort of infants born < 28 weeks gestational age. QoL was assessed at 10 years of age using the Pediatric Quality of Life Inventory. Multivariate regression models were used for analyses.

Results

Of 1198 participants who survived until 10 years of age, 889 (72.2%) were evaluated. Lower maternal age, lack of college education; receipt of public insurance and Supplemental Nutrition Assistance Program (SNAP) were associated with lower QoL scores. Specific maternal health factors were also associated with lower child QoL scores.

Conclusions

Specific, potentially modifiable, maternal health and social factors are associated with lower scores on a measure of parent-reported child QoL across multiple domains for children born extremely preterm.