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Urinary tract infections in very premature neonates: the definition dilemma

  • 期刊论文

  • 发表日期：

    2024年3月29日

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  • Assil Abda,
  • Luc Panetta,
  • Julie Blackburn,
  • Isabelle Chevalier,
  • Christian Lachance,
  • Philippe Ovetchkine,
  • Melanie Sicard

摘要

Background and objectives

Data on urinary tract infections (UTIs) in very preterm neonates (VPTNs) are scarce. We aimed to (i) describe the characteristics of UTIs in VPTNs and (ii) compare the diagnostic practices of neonatal clinicians to established pediatric guidelines.

Methods

All VPTNs (<29 weeks GA) with a suspected UTI at the CHU Sainte-Justine neonatal intensive care unit from January 1, 2014, and December 31, 2019, were included and divided into two definition categories: Possible UTI, and Definite UTI.

Results

Most episodes were Possible UTI (87%). Symptoms of UTIs and pathogens varied based on the definition category. A positive urinalysis was obtained in 25%. Possible UTI episodes grew 2 organisms in 62% of cases and <50,000 CFU/mL in 62% of cases.

Conclusion

Characteristics of UTIs in VPTNs vary based on the definition category and case definitions used by clinicians differ from that of established pediatric guidelines.