<p>Obesity management has traditionally focused on diet, physical activity, and medical interventions, while emotional and relational factors such as compassion, connection, and the reduction of shame remain underemphasized. Emerging evidence highlights the roles of love and compassion—defined as care, connection, and kindness toward oneself and others—as potential catalysts for sustainable lifestyle change. Compassion-based approaches reduce shame, stigma, and emotional dysregulation, thereby supporting self-care and motivation. This Perspective advances the view that integrating love and compassion into obesity treatment offers a more humane and potentially more effective framework for improving health and well-being among individuals living with obesity.</p>