<p>Obesity/adiposity, an often-intractable disease with serious physical, economic, and societal consequences, is a major problem for health practitioners. Despite extensive research, obesity remains a kind of pandemic. There is significant evidence that individuals with obesity react to both fat-soluble and water-soluble vitamin levels in their serum. Vitamins correlate negatively with body weight, body mass index, and body composition. Certain vitamins may possess anti-adipogenic, anti-inflammatory, and antioxidant properties. Yet still, there is no consensus among researchers about the general impact of vitamins on obesity. A clearer understanding of the effects of vitamins on obesity will make dietary interventions more effective in preventing and treating obesity and its complications. This article analyses the current data about the impact of vitamins on controlling obesity, including their role, action mechanisms and obesity-related metabolic statuses. Such an analysis could enhance our understanding of the effects of vitamins on obesity. So, this article could assist future researchers who are working toward better protocols for treating obesity.</p><p></p>