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Objectives <p>We investigated p-wave dispersion (Pd) and atrial electromechanical delay (EMD) in patients diagnosed with non-obstructive coronary artery disease and myocardial infarction (MINOCA).</p> Background <p>The clinical importance and recognition of MINOCA are increasing. However, there is a gap in knowledge regarding the risk of atrial fibrillation in patients with MINOCA.</p> Methods <p>Forty-three patients with MINOCA (average age 48.69 ± 5.83&#xa0;years) and thirty-four patients with non-obstructed coronary artery disease (INOCA) (average age 49.82 ± 10.22&#xa0;years) were enrolled in the study. Echocardiographic studies were conducted in the MINOCA and INOCA groups in the left lateral decubitus position using a medical ultrasound device. Atrial electromechanical coupling (PA) and intra-atrial and interatrial EMD were measured using tissue Doppler echocardiography. Pd was measured using 12-lead electrocardiography.</p> Results <p>Clinical and demographic characteristics were similar between groups. The maximum P-wave (Pmax) time and Pd values of patients diagnosed with MINOCA were significantly longer than those of patients diagnosed with INOCA (Pmax times: 109.72 ± 7.09&#xa0;ms and 95.17 ± 7.50&#xa0;ms, respectively, p &lt; 0.01; Pd: 47.30 ± 8.99&#xa0;ms and 34.14 ± 11.31&#xa0;ms, respectively, p &lt; 0.01). Tissue Doppler Imaging (TDI) revealed significantly longer atrial EMD parameters (PA lateral and PA septum) in patients diagnosed with MINOCA than in those diagnosed with INOCA (69.60 ± 8.79&#xa0;ms and 57.08 ± 11.54&#xa0;ms, respectively, p &lt; 0.01; 54.83 ± 6.45&#xa0;ms and 45.35 ± 8.50&#xa0;ms, respectively, p &lt; 0.01).</p> Conclusion <p>This study showed that the duration of atrial EMD and Pd was prolonged in patients with MINOCA, suggesting a potential susceptibility to atrial conduction abnormalities.</p>

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Assessment of P-Wave Dispersion and Atrial Electromechanical Delay in Patients with Non-Obstructive Coronary Artery Myocardial Infarction

  • 期刊论文

  • 发表日期：

    2025年8月27日

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  • Saban Kelesoglu,
  • Yucel Yilmaz,
  • Deniz Elcik,
  • Sinan Inci,
  • Murat Gul,
  • Nihat Kalay

摘要

Objectives

We investigated p-wave dispersion (Pd) and atrial electromechanical delay (EMD) in patients diagnosed with non-obstructive coronary artery disease and myocardial infarction (MINOCA).

Background

The clinical importance and recognition of MINOCA are increasing. However, there is a gap in knowledge regarding the risk of atrial fibrillation in patients with MINOCA.

Methods

Forty-three patients with MINOCA (average age 48.69 ± 5.83 years) and thirty-four patients with non-obstructed coronary artery disease (INOCA) (average age 49.82 ± 10.22 years) were enrolled in the study. Echocardiographic studies were conducted in the MINOCA and INOCA groups in the left lateral decubitus position using a medical ultrasound device. Atrial electromechanical coupling (PA) and intra-atrial and interatrial EMD were measured using tissue Doppler echocardiography. Pd was measured using 12-lead electrocardiography.

Results

Clinical and demographic characteristics were similar between groups. The maximum P-wave (Pmax) time and Pd values of patients diagnosed with MINOCA were significantly longer than those of patients diagnosed with INOCA (Pmax times: 109.72 ± 7.09 ms and 95.17 ± 7.50 ms, respectively, p < 0.01; Pd: 47.30 ± 8.99 ms and 34.14 ± 11.31 ms, respectively, p < 0.01). Tissue Doppler Imaging (TDI) revealed significantly longer atrial EMD parameters (PA lateral and PA septum) in patients diagnosed with MINOCA than in those diagnosed with INOCA (69.60 ± 8.79 ms and 57.08 ± 11.54 ms, respectively, p < 0.01; 54.83 ± 6.45 ms and 45.35 ± 8.50 ms, respectively, p < 0.01).

Conclusion

This study showed that the duration of atrial EMD and Pd was prolonged in patients with MINOCA, suggesting a potential susceptibility to atrial conduction abnormalities.