Background <p>This study aimed to examine the relationship of individual anthropometric parameters with the severity of sleep apnea (SA), type of SA, positive airway pressure (PAP) titration pressures, and titration effectivity.</p> Methods <p>We have included previously healthy patients, who were suspected of suffering from sleep apnea and were hospitalized in the sleep laboratory. All subjects underwent overnight polysomnography, followed by PAP titration in patients with moderate-to-severe sleep apnea (AHI ≥ 15/h). Basic anthropometric examination and body composition evaluation using the InBody 720 device were performed.</p> Results <p>Among 40 previously healthy male subjects, we found statistically significant correlations between almost all body composition parameters and sleep apnea-related indices. No significant differences in these parameters were found between obstructive and central SA. In the obstructive SA group, the degree of obesity and multiple other obesity markers positively correlated with higher titration PAP pressures. Contrary to obstructive SA, in the central SA group, higher titration PAP pressures correlated only with body fat percentage and waist-to-hip ratio. In both groups, no significant positive correlation between residual apnea/hypopnea index during PAP titration and anthropometric measures was found.</p> Conclusion <p>Patients with central and obstructive SA did not differ significantly in anthropometric parameters. Despite significant correlations between almost all anthropometric parameters and sleep apnea-related indices, as well as with titration PAP pressures, our findings suggest, that obesity does not significantly contribute to the&#xa0;PAP titration failure represented by residual respiratory events.</p>

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Anthropometric Parameters and Sleep Apnea: Correlations, and Treatment Implications in a Sleep Laboratory-Based Study

  • Branislav Kollár,
  • Pavel Šiarnik,
  • Lenka Matejáková,
  • Martin Soldán,
  • Michal Poddaný,
  • Katarína Klobučníková,
  • Peter Turčáni,
  • Ľubica Argalášová

摘要

Background

This study aimed to examine the relationship of individual anthropometric parameters with the severity of sleep apnea (SA), type of SA, positive airway pressure (PAP) titration pressures, and titration effectivity.

Methods

We have included previously healthy patients, who were suspected of suffering from sleep apnea and were hospitalized in the sleep laboratory. All subjects underwent overnight polysomnography, followed by PAP titration in patients with moderate-to-severe sleep apnea (AHI ≥ 15/h). Basic anthropometric examination and body composition evaluation using the InBody 720 device were performed.

Results

Among 40 previously healthy male subjects, we found statistically significant correlations between almost all body composition parameters and sleep apnea-related indices. No significant differences in these parameters were found between obstructive and central SA. In the obstructive SA group, the degree of obesity and multiple other obesity markers positively correlated with higher titration PAP pressures. Contrary to obstructive SA, in the central SA group, higher titration PAP pressures correlated only with body fat percentage and waist-to-hip ratio. In both groups, no significant positive correlation between residual apnea/hypopnea index during PAP titration and anthropometric measures was found.

Conclusion

Patients with central and obstructive SA did not differ significantly in anthropometric parameters. Despite significant correlations between almost all anthropometric parameters and sleep apnea-related indices, as well as with titration PAP pressures, our findings suggest, that obesity does not significantly contribute to the PAP titration failure represented by residual respiratory events.