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<p>Chronic low back pain (CLBP) related to dynamic lumbar instability represents a major global health burden. Although lumbosacral fusion remains a standard surgical treatment, important limitations such as loss of physiological motion, paraspinal muscle atrophy, and accelerated adjacent segment disease have motivated the development of motion-preserving alternatives. This comprehensive review synthesizes recent translational engineering advances in dynamic spinal stabilization, with particular emphasis on mechanically tunable implants and integrated biomechanical feedback systems. Key developments include bioadaptive polymeric and hybrid constructs designed to better replicate native viscoelastic spinal behavior, finite element modeling approaches used to optimize implant stiffness and load sharing, and emerging soft robotic concepts that enable patient-specific and activity-dependent modulation of stabilizing forces. In parallel, advances in embedded microelectromechanical and nanosensor technologies now allow real-time, in vivo monitoring of implant strain, intradiscal pressure, and segmental spinal kinematics, creating opportunities for adaptive, feedback-driven stabilization strategies. Collectively, these innovations support a shift from static fixation toward responsive spinal implants that preserve motion while maintaining stability. For clinicians, such systems may reduce the risk of adjacent segment degeneration and allow for more individualized postoperative rehabilitation. For researchers, they highlight the need for continued work in material durability, sensor reliability, power management, and regulatory translation. Progress in these areas, supported by rigorous preclinical validation and clinical trials, may ultimately reshape the surgical management of lumbar instability.</p>

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Dynamic spine stabilization through mechanically tuned constructs and embedded biomechanical feedback systems: a narrative review

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年4月20日

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  • Rahul Kumar,
  • Andrew Bouras,
  • Rohan Phadke,
  • Samer Salman,
  • Harlene Kaur,
  • Kyle Sporn,
  • Alejandro Damian,
  • Phani Paladugu,
  • Swapna Vaja,
  • Alireza Tavakkoli,
  • Nathan J. Lee

摘要

Chronic low back pain (CLBP) related to dynamic lumbar instability represents a major global health burden. Although lumbosacral fusion remains a standard surgical treatment, important limitations such as loss of physiological motion, paraspinal muscle atrophy, and accelerated adjacent segment disease have motivated the development of motion-preserving alternatives. This comprehensive review synthesizes recent translational engineering advances in dynamic spinal stabilization, with particular emphasis on mechanically tunable implants and integrated biomechanical feedback systems. Key developments include bioadaptive polymeric and hybrid constructs designed to better replicate native viscoelastic spinal behavior, finite element modeling approaches used to optimize implant stiffness and load sharing, and emerging soft robotic concepts that enable patient-specific and activity-dependent modulation of stabilizing forces. In parallel, advances in embedded microelectromechanical and nanosensor technologies now allow real-time, in vivo monitoring of implant strain, intradiscal pressure, and segmental spinal kinematics, creating opportunities for adaptive, feedback-driven stabilization strategies. Collectively, these innovations support a shift from static fixation toward responsive spinal implants that preserve motion while maintaining stability. For clinicians, such systems may reduce the risk of adjacent segment degeneration and allow for more individualized postoperative rehabilitation. For researchers, they highlight the need for continued work in material durability, sensor reliability, power management, and regulatory translation. Progress in these areas, supported by rigorous preclinical validation and clinical trials, may ultimately reshape the surgical management of lumbar instability.