<p>Globally, climate change-induced stresses have continued to threaten the growth of food crops. Among the stresses, drought has been known to be outstanding due to its macro and micro complications on the growth of food crops. To avert this drought stress challenge, drought stress-tolerant crop-based breeding technology put in place has achieved little success while transgenic crops have drawbacks due to biosafety regulations and public acceptance in many countries. Going forward, rhizobacteria have received global attention due to the fact that they are eco-friendly, environmentally safe, and cost-effective, thereby enhancing crop productivity. Specifically, some rhizobacteria have the potential to leverage their interaction with the crop plants to readjust their activities and mechanisms to enhance the adaptation of the crop plant to drought stress. Unfortunately, there is a lack of information on their genomics in the context of their genome sequences as a guiding light towards accurate identification of the drought stress-tolerant rhizobacteria, as well as the genes involved in their functional traits geared towards unfolding their drought stress tolerance mechanisms for sustainable growth of food crops. On this note, this review discusses the global relevance of beneficial drought stress-tolerant rhizobacteria and why the genome sequences of rhizobacteria are a priority for the sustainable growth of food crops. This review further elaborates on the key genes in the rhizobacteria genome, their functional traits, and mechanisms of action in host crops geared towards sustainable growth of food crops under climate change-induced drought stress.</p>