Right ventricular dysfunction in critically ill patients; TAPSE and RV-TDs as applicable accurate predictors of right ventricular dysfunction: a prospective study in Egypt
摘要
To assess the impact of RV dysfunction on hospital stay and mortality and to assess the accuracy of different echocardiographic parameters of RV dysfunction.
MethodsA prospective study was conducted at Critical Care Unit of Assiut University Hospital. Echocardiography was performed within the first 48 h of admission and repeated on the 5–7 days of admission.
ResultsThe study enrolled 200 critically ill patients. A total of 50 (25%) patients developed RV dysfunction (RVD group). RVD group had significantly higher mean age (67.98 ± 10.56 vs. 51.75 ± 7.89 (years); p < 0.001) and the majority of patients were males. The most frequent cause of admission in patients with RVD was septic shock (38%). At “cutoff” point < 17 mm, TAPSE had the best diagnostic accuracy (91.8%) for predicting RVD in critically ill patients followed by right ventricle tissue Doppler (RV-TDs) which had 87.8% accuracy at cutoff point < 9.50 cm/s. RV-fractional area change had the least accuracy (66.3%) at cut off point < 35%, which was not statistically significant (p = 0.19). Patients with RVD had significantly longer hospital stay (19.33 ± 3.49 vs. 12.44 ± 4.09 (days); p < 0.001) and higher frequency of mortality (30% vs. 14%). The predictors of mortality among the studied patients were RVD, low serum albumin, need to mechanical ventilation, APACHE-IV and SOFA scores.
ConclusionPatients with right ventricle dysfunction during their admission have longer length of stay and higher frequency of mortality. TAPSE and RV-TDs were the most accurate echocardiographic findings for RVD.