Scholarlink

Background <p>Human Metapneumovirus (HMPV) is a globally circulating respiratory pathogen primarily affecting children, the elderly, and immunocompromised individuals. Since its discovery in 2001, HMPV has been increasingly recognized as a significant cause of acute respiratory tract infections (ARTIs). Despite its clinical burden, no approved vaccines or antiviral treatments exist, and management remains supportive. The resurgence of HMPV and its potential to cause pandemics, particularly in the post-COVID-19 era, highlights the urgent need for improved surveillance and targeted interventions.</p> Main body <p>This systematic review follows PRISMA guidelines, analyzing literature from PubMed, Scopus, and Web of Science published between 2000 and 2025 to highlight the pandemic potential of HMPV, especially in the post-COVID-19 era, and also to explore key areas where advancements are needed to curtail such pandemics if they may happen. Specifically, we aim to evaluate the diagnostic challenges, as well as recent advances in detection methods, emerging therapeutic strategies, and the evolving epidemiological patterns of HMPV in relation to the virus being a potential threat of causing pandemics.</p> Conclusion <p>HMPV remains a critical public health concern due to its recurrent outbreaks, recent resurgence, and its potential to cause pandemics. Strengthening diagnostic surveillance, fostering research collaborations, and expediting vaccine development are imperative. Public health preparedness and infection control measures must be reinforced to mitigate HMPV’s impact in the imminent possibility of a global pandemic, as well as its disastrous outcome among high-risk populations in endemic regions.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Human Metapneumovirus: an emerging threat in respiratory viral infections and a public health concern

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月1日

查看全文
  • Abubakar Sunusi Ishak,
  • Auwal Rabiu Auwal,
  • Adamu Safiyanu Maikifi,
  • Shuaibu Saidu Musa,
  • M. M. Dalhatu,
  • Abbas Musa,
  • Anila Riaz

摘要

Background

Human Metapneumovirus (HMPV) is a globally circulating respiratory pathogen primarily affecting children, the elderly, and immunocompromised individuals. Since its discovery in 2001, HMPV has been increasingly recognized as a significant cause of acute respiratory tract infections (ARTIs). Despite its clinical burden, no approved vaccines or antiviral treatments exist, and management remains supportive. The resurgence of HMPV and its potential to cause pandemics, particularly in the post-COVID-19 era, highlights the urgent need for improved surveillance and targeted interventions.

Main body

This systematic review follows PRISMA guidelines, analyzing literature from PubMed, Scopus, and Web of Science published between 2000 and 2025 to highlight the pandemic potential of HMPV, especially in the post-COVID-19 era, and also to explore key areas where advancements are needed to curtail such pandemics if they may happen. Specifically, we aim to evaluate the diagnostic challenges, as well as recent advances in detection methods, emerging therapeutic strategies, and the evolving epidemiological patterns of HMPV in relation to the virus being a potential threat of causing pandemics.

Conclusion

HMPV remains a critical public health concern due to its recurrent outbreaks, recent resurgence, and its potential to cause pandemics. Strengthening diagnostic surveillance, fostering research collaborations, and expediting vaccine development are imperative. Public health preparedness and infection control measures must be reinforced to mitigate HMPV’s impact in the imminent possibility of a global pandemic, as well as its disastrous outcome among high-risk populations in endemic regions.