Scholarlink

<p>High Altitude Cerebral Edema (HACE) is a potentially fatal brain disease associated with the Hypobaric Hypoxia (HH) environment, and its development is dependent on the duration of hypoxia. Under certain levels of hypoxia, HACE can cause clinical symptoms such as headache, nausea, vomiting, ataxia, and disturbance of consciousness. If not treated promptly or appropriately, it may lead to coma and brain herniation, thus threatening life. Given that the pathogenesis of HACE has not been fully elucidated and traditional treatment methods have limitations, this paper aims to review the latest progress in the treatment of HACE and discuss in detail the preventive or protective mechanisms, with a view to providing new strategies for the treatment and prevention of HACE.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Multifaceted therapeutic mechanisms underlying high altitude cerebral edema: a systematic review

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月15日

查看全文
  • Shiwang Li,
  • Shizeng Li,
  • Hongling Guan,
  • E. Lu,
  • Dahai Cao,
  • Qiang Zhang

摘要

High Altitude Cerebral Edema (HACE) is a potentially fatal brain disease associated with the Hypobaric Hypoxia (HH) environment, and its development is dependent on the duration of hypoxia. Under certain levels of hypoxia, HACE can cause clinical symptoms such as headache, nausea, vomiting, ataxia, and disturbance of consciousness. If not treated promptly or appropriately, it may lead to coma and brain herniation, thus threatening life. Given that the pathogenesis of HACE has not been fully elucidated and traditional treatment methods have limitations, this paper aims to review the latest progress in the treatment of HACE and discuss in detail the preventive or protective mechanisms, with a view to providing new strategies for the treatment and prevention of HACE.