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Background <p>Appendix carcinoma is a rare type of cancer, accounting for about approximately 0.5% of all gastrointestinal tumors. The atypical presentation of appendix carcinoma complicates early detection and subsequent treatment. Therefore, it is crucial to raise awareness of this rare cancer type and promote early diagnostic measures.</p> Case presentation <p>This article presents the case of a young patient who initially exhibited typical appendicitis symptoms. However, postoperative histopathological analysis revealed a neuroendocrine tumor (NET G1pT1). The case is discussed in comparison with relevant literature and clinical American and European guidelines, highlighting the importance of intraoperative histopathological examination. Regardless of the patient´s age, family history, or symptom presentation, early and accurate diagnosis is critical for determining prognosis and guiding management.</p> Conclusion <p>A standardized approach for detecting appendix neoplasms, incorporating imaging, endoscopy, and follow-up, is recommended to improve diagnostic accuracy, treatment outcomes, and long-term survival. This case underscores the importance of a multidisciplinary approach and comprehensive post-operative evaluation. Additionally, reporting clinical cases like this contributes to refining clinical guidelines and advancing understanding, aligning with both American and European recommendations to optimize patient care.</p>

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Neuroendocrine tumor of the appendix: an incidental clinic finding

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年6月25日

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  • Pedro Beltran Lopez,
  • Caroline Beltran Lopez,
  • Stefan Schopf,
  • Thomas von Ahnen

摘要

Background

Appendix carcinoma is a rare type of cancer, accounting for about approximately 0.5% of all gastrointestinal tumors. The atypical presentation of appendix carcinoma complicates early detection and subsequent treatment. Therefore, it is crucial to raise awareness of this rare cancer type and promote early diagnostic measures.

Case presentation

This article presents the case of a young patient who initially exhibited typical appendicitis symptoms. However, postoperative histopathological analysis revealed a neuroendocrine tumor (NET G1pT1). The case is discussed in comparison with relevant literature and clinical American and European guidelines, highlighting the importance of intraoperative histopathological examination. Regardless of the patient´s age, family history, or symptom presentation, early and accurate diagnosis is critical for determining prognosis and guiding management.

Conclusion

A standardized approach for detecting appendix neoplasms, incorporating imaging, endoscopy, and follow-up, is recommended to improve diagnostic accuracy, treatment outcomes, and long-term survival. This case underscores the importance of a multidisciplinary approach and comprehensive post-operative evaluation. Additionally, reporting clinical cases like this contributes to refining clinical guidelines and advancing understanding, aligning with both American and European recommendations to optimize patient care.