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<p>Classified as a lymphotropic virus, Epstein–Barr virus (EBV) is a ubiquitous pathogen responsible for infectious mononucleosis that usually presents in childhood and is typically self-limiting. In adults, infection with EBV remains a diagnostic challenge given the vast array of clinical presentations, from mild symptoms such as malaise and dyspnea to severe outcomes like myocardial infarction. Atherosclerotic plaques within the coronary arteries contain inflammatory cells and can become activated in the setting of acute infections by chemokines and cytokines such as interleukin-6 and interleukin-8. Combined with endothelial dysfunction and platelet aggregation, subsequent coronary thrombosis results in the lack of oxygen delivery to myocardial tissues. We report a case of EBV-associated post-infectious MI in a patient who presented with chest pain that ultimately resulted in cardiogenic shock.</p>

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Post-infectious myocardial infarction due to Epstein–Barr virus: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月9日

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  • Julie Martino,
  • Ian Quiroz,
  • Sean Martin,
  • Michael Kaunas,
  • Zane Elfessi

摘要

Classified as a lymphotropic virus, Epstein–Barr virus (EBV) is a ubiquitous pathogen responsible for infectious mononucleosis that usually presents in childhood and is typically self-limiting. In adults, infection with EBV remains a diagnostic challenge given the vast array of clinical presentations, from mild symptoms such as malaise and dyspnea to severe outcomes like myocardial infarction. Atherosclerotic plaques within the coronary arteries contain inflammatory cells and can become activated in the setting of acute infections by chemokines and cytokines such as interleukin-6 and interleukin-8. Combined with endothelial dysfunction and platelet aggregation, subsequent coronary thrombosis results in the lack of oxygen delivery to myocardial tissues. We report a case of EBV-associated post-infectious MI in a patient who presented with chest pain that ultimately resulted in cardiogenic shock.