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<p>This commentary highlights the transformative potential of liquid biopsies in neuropsychiatric disorders, focusing on circulating cell-free DNA (ccfDNA) as a diagnostic and monitoring biomarker. By discussing advances in epigenetic profiling, integration with complementary biomarkers, and addressing pre-analytical challenges, the commentary underscores the promise of these tools in advancing precision medicine. Future research directions emphasize the need for large-scale studies, scalable platforms, and interdisciplinary collaboration to translate findings into clinical practice.</p>

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Commentary on: Liquid Biopsy in Neuropsychiatric Disorders: A Step Closer to Precision Medicine

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年6月23日

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  • Asael Lubotzky

摘要

This commentary highlights the transformative potential of liquid biopsies in neuropsychiatric disorders, focusing on circulating cell-free DNA (ccfDNA) as a diagnostic and monitoring biomarker. By discussing advances in epigenetic profiling, integration with complementary biomarkers, and addressing pre-analytical challenges, the commentary underscores the promise of these tools in advancing precision medicine. Future research directions emphasize the need for large-scale studies, scalable platforms, and interdisciplinary collaboration to translate findings into clinical practice.