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<p>Blue toe syndrome (BTS) is characterized by an acute onset of often painful, blue/violaceous discoloration of one or multiple toes due to impaired blood flow, leading to ischemia of the affected digits. There are a plethora of etiologies of BTS that can be broadly classified into several factors: vascular obstruction, autoimmune conditions, hyperviscosity syndromes, infections, drug-induced occurrences, and vasospasm. In this review, we aimed to provide clinicians with an understanding of the etiologies of BTS and provide an approach to a patient presenting with BTS.</p>

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A review and approach to the diagnosis of blue toe syndrome

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年3月17日

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  • Melika Motamedi,
  • Jadin Chahade,
  • Robert Gniadecki,
  • Elaine Yacyshyn

摘要

Blue toe syndrome (BTS) is characterized by an acute onset of often painful, blue/violaceous discoloration of one or multiple toes due to impaired blood flow, leading to ischemia of the affected digits. There are a plethora of etiologies of BTS that can be broadly classified into several factors: vascular obstruction, autoimmune conditions, hyperviscosity syndromes, infections, drug-induced occurrences, and vasospasm. In this review, we aimed to provide clinicians with an understanding of the etiologies of BTS and provide an approach to a patient presenting with BTS.