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Background <p>Cataract&#xa0;is the most prevalent cause of blindness and the second most common cause of visual impairment globally. The primary cause of blindness in Ethiopia is cataracts. However, there is no evidence of pooled prevalence. The aim of this study was to assess the burden and determinants of cataract among adult people aged 40&#xa0;years and above in Ethiopia.</p> Methods <p>Potential studies were chosen using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. PubMed, scopes and web of science were searched to identify relevant studies from 2000 to 2024 GC. To examine for heterogeneity the I<sup>2</sup> statistic was employed. A random-effects model was applied to estimate the pooled effect size across studies. The Egger's regression test and a funnel plot were employed to look for evidence of publication bias. The quality of included studies was assessed by utilizing the Newcastle–Ottawa Scale. The pooled burden and determinants of cataract were determined using STATA 17.0.</p> Results <p>A total of 5 studies met the inclusion criteria. In 2024, the pooled overall burden of cataract in 2989 people was 36% (95%CI 14–58%). Based on subgroup analysis, in the random effect method, the frequency of cataract in males and females were 17% (95% CI 0.07, 0.42) and 20% (95% CI 0.04, 0.36), respectively. The burden of cataract also in participants aged 40–49&#xa0;years and older was found to be 6% (95% CI 0.04, 0.07) and 40% (95% CI 0.04, 0.75) correspondingly. Participants with a single marital status (AOR = 4.59, 95% CI 2.01, 7.17) and individuals 70&#xa0;years of age and older (AOR = 7.35, 95% CI (2.93, 11.77)) have a higher risk of having cataract.</p> Conclusions <p>A considerable proportion of research participants were found to have cataracts. Two factors were linked to cataract development: age and single marital status. Better cataract control in Ethiopia may arise from heeding the findings of the current study and putting international policy initiatives into practice.</p>

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Burden and determinants of cataract among adult patients over 40 years old in Ethiopia: a systematic review and meta-analysis, 2024

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  • 发表日期：

    2025年3月21日

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  • Kedir Seid,
  • Gebeyehu Lakew,
  • Amlaku Nigusie Yirsaw,
  • Natnael Kebede,
  • Mitiku Tefera,
  • Eyob Ketema Bogale,
  • Tadele Fentabel Anagaw,
  • Misganaw Guadie Tiruneh,
  • Eneyew Talie Fenta,
  • Destaw Endeshaw,
  • Ousman Adal,
  • Abiyu Abadi Tareke,
  • Lijalem Jenberu,
  • Eyob Getachew,
  • Asnake Gashaw Belayneh,
  • Getnet Alemu Andargie

摘要

Background

Cataract is the most prevalent cause of blindness and the second most common cause of visual impairment globally. The primary cause of blindness in Ethiopia is cataracts. However, there is no evidence of pooled prevalence. The aim of this study was to assess the burden and determinants of cataract among adult people aged 40 years and above in Ethiopia.

Methods

Potential studies were chosen using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. PubMed, scopes and web of science were searched to identify relevant studies from 2000 to 2024 GC. To examine for heterogeneity the I2 statistic was employed. A random-effects model was applied to estimate the pooled effect size across studies. The Egger's regression test and a funnel plot were employed to look for evidence of publication bias. The quality of included studies was assessed by utilizing the Newcastle–Ottawa Scale. The pooled burden and determinants of cataract were determined using STATA 17.0.

Results

A total of 5 studies met the inclusion criteria. In 2024, the pooled overall burden of cataract in 2989 people was 36% (95%CI 14–58%). Based on subgroup analysis, in the random effect method, the frequency of cataract in males and females were 17% (95% CI 0.07, 0.42) and 20% (95% CI 0.04, 0.36), respectively. The burden of cataract also in participants aged 40–49 years and older was found to be 6% (95% CI 0.04, 0.07) and 40% (95% CI 0.04, 0.75) correspondingly. Participants with a single marital status (AOR = 4.59, 95% CI 2.01, 7.17) and individuals 70 years of age and older (AOR = 7.35, 95% CI (2.93, 11.77)) have a higher risk of having cataract.

Conclusions

A considerable proportion of research participants were found to have cataracts. Two factors were linked to cataract development: age and single marital status. Better cataract control in Ethiopia may arise from heeding the findings of the current study and putting international policy initiatives into practice.