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<p>Glomus tumors (GT) are benign but confounding pathologies harbored in the skull base, occupying critical locations like the middle ear, jugular foramen and carotid bifurcation. They are highly vascular tumors that commonly present with locally advanced disease, infiltrating lower cranial nerves thereby disparaging the prospect of surgery due to possible complications. Conventional radiotherapy in form of external beam radiotherapy and intensity modulated radiotherapy offered promise for tumor control; however, this was an unacceptable trade-off with the side effects accompanying these modalities. Over the years, stereotactic surgery (SRS) has garnered an unswerving consensus as a standalone and adjunctive therapy for GT. We discuss our philosophy of treating this pathology in the background of evolving literature on Gamma Knife surgery for GT. We aim to address diagnostic and therapeutic dilemmas surrounding GT to aid clinicians in decision making.</p>

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SRS for glomus tumors: a sophisticated solution for a benign yet confounding pathology

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年1月29日

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  • Onam Verma,
  • Syed Yasin Shahtaz Emanee,
  • Rupinder Kaur,
  • Manjul Tripathi

摘要

Glomus tumors (GT) are benign but confounding pathologies harbored in the skull base, occupying critical locations like the middle ear, jugular foramen and carotid bifurcation. They are highly vascular tumors that commonly present with locally advanced disease, infiltrating lower cranial nerves thereby disparaging the prospect of surgery due to possible complications. Conventional radiotherapy in form of external beam radiotherapy and intensity modulated radiotherapy offered promise for tumor control; however, this was an unacceptable trade-off with the side effects accompanying these modalities. Over the years, stereotactic surgery (SRS) has garnered an unswerving consensus as a standalone and adjunctive therapy for GT. We discuss our philosophy of treating this pathology in the background of evolving literature on Gamma Knife surgery for GT. We aim to address diagnostic and therapeutic dilemmas surrounding GT to aid clinicians in decision making.