Scholarlink

<p>Central nervous system tuberculosis is an uncommon but serious form of extrapulmonary tuberculosis and remains a diagnostic challenge due to its variable and often atypical imaging appearance. En-plaque tuberculoma is a rare manifestation that may mimic other dural-based pathologies. Report the case of a 35-year-old male patient who presented with a discharging sinus and an underlying scalp abscess in the left parietal region, associated with chronic headache. Routine laboratory investigations, cerebrospinal fluid analysis and sputum examination were within normal limits. Contrast-enhanced MRI demonstrated an en-plaque dural-based lesion along the left parietal convexity, showing hypointensity on T2-weighted images, restricted diffusion, heterogeneous post-contrast enhancement, marked vasogenic oedema, adjacent subdural empyema, calvarial erosion and communication with an extracranial scalp abscess. The patient underwent craniotomy with excision of the lesion and involved dura. Histopathological examination revealed caseating granulomatous inflammation consistent with tuberculoma. The patient was started on anti-tubercular therapy and showed complete clinical resolution of discharging sinus, with no residual lesion on 6-month follow-up MRI. This case highlights an unusual presentation of an en-plaque tuberculoma with extracranial extension. This can aid in timely management and reduce morbidity and mortality related to the disease.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

En-plaque tuberculoma: an uncommon cause of dural-based mass

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月20日

查看全文
  • Mitalee Garg,
  • Soumya Ranjan Nayak,
  • Vajrala Vineela Shambhavi,
  • Somadatta Das

摘要

Central nervous system tuberculosis is an uncommon but serious form of extrapulmonary tuberculosis and remains a diagnostic challenge due to its variable and often atypical imaging appearance. En-plaque tuberculoma is a rare manifestation that may mimic other dural-based pathologies. Report the case of a 35-year-old male patient who presented with a discharging sinus and an underlying scalp abscess in the left parietal region, associated with chronic headache. Routine laboratory investigations, cerebrospinal fluid analysis and sputum examination were within normal limits. Contrast-enhanced MRI demonstrated an en-plaque dural-based lesion along the left parietal convexity, showing hypointensity on T2-weighted images, restricted diffusion, heterogeneous post-contrast enhancement, marked vasogenic oedema, adjacent subdural empyema, calvarial erosion and communication with an extracranial scalp abscess. The patient underwent craniotomy with excision of the lesion and involved dura. Histopathological examination revealed caseating granulomatous inflammation consistent with tuberculoma. The patient was started on anti-tubercular therapy and showed complete clinical resolution of discharging sinus, with no residual lesion on 6-month follow-up MRI. This case highlights an unusual presentation of an en-plaque tuberculoma with extracranial extension. This can aid in timely management and reduce morbidity and mortality related to the disease.